E-Pledge
April 13, 2008 | 52°F Overcast

Radiolab

Mix and Match

To get us thinking about creating new life forms, we tag along with a group of kids on a visit to the American Museum of Natural History exhibit on Mythic Creatures. Curator Laurel Kendall tells us that even figments of the human imagination deserve to be a part of natural history. But what do we mean when we say something is "natural?" Sometimes nature does things that might seem unnatural, at least at first glance. Karen Keegan and her doctor Lynne Uhl tell reporter Soren Wheeler a story of disputed motherhood that might throw your idea of natural for a loop. (Hint: Karen is more than one person, kind of.) Then we enter the world of bioengineering with scientist Lee Silver from Princeton University. Silver tells us about a strange creature created by scientists back in the 80s, called a "geep." And then he tells us about a very disturbing real-life incident that playwright Jeremy Kareken, in collaboration with Dr. Silver, turned into a play about the implications of combining humans and other animals.

American Museum of Natural History, Mythic Creatures Exhibit
An Article about Karen and another Chimera Mother
A National Geographic Article about Chimeras
Lee Silver’s Website
Buy a Pegasus Wing


Listener Comments Comment | Refresh | Back to Episode
[1]
Posted by: Scott McVicker
February 26, 2008 - 01:44PM
Half Moon Bay, California

Re: Karen Keegan. Two tests I would have liked to see - A comparison between Karen's two DNA samples with that of her parents, and the same test of her children relative to their grandparents.

[2]
Posted by: Soren Wheeler
March 06, 2008 - 10:34AM

Scott,

The doctors did compare the son's DNA to Karen's mother and two brother, though unfortunately Karen's father had passed away by that time. And they did find that the sons were related to her larger family. To my knowledge, they never compared Karen's second set of DNA to the family, I believe beceause they felt the twin explanation was pretty clear and they didn't want to keep poking and prodding Karen.

Soren.

[3]
Posted by: Alison
March 06, 2008 - 04:05PM
Minnesota

I'm transgendered. I wonder if anyone has explored the idea that perhaps transgendered people could be chimeras. Could I actually have the DNA of both a man and a woman in me? Has anyone heard of research into this?

[4]
Posted by: Jeremy Kareken
March 08, 2008 - 02:38PM
New York

TGAlison: It's not likely but certainly possible. Chimerism includes a number of specific intersexual conditions and a simple DNA test will check. I'm curious: what parts do you think are those of your never-born fraternal sister? Or brother?

TG is even less specific than "chimerism," because it's not a medical diagnosis, but a social rubric, and rather a broad one at that. There are all sorts of medical conditions that can encourage gender identity issues - adrenal hyperplasia, androgen sensitivity, hermaphoditism. And there are people who just like to play dress-up who call themselves TG.

Now hermaphroditism can be a symptom of chimerism, but you can be certain through DNA testing. One generally sees skin abnormalities in cases of chimerism. They follow what are called "Blaschko's Lines." And certainly other intersexual components occur, like testes in some women, ovaries in men, or ovotestes, and the like...

[5]
Posted by: James The Giant Peach
March 14, 2008 - 03:44PM
Park Slope

where can we see pictures of the Geep?

[6]
Posted by: Blake
March 23, 2008 - 12:35AM

I'd love to listen to this show, but I can't find the audio link anywhere, even though the show was a week ago. Could someone post it, or be so kind as to tell me how to find it? (Apologies in advance if it is obvious and I am somehow missing it.)

[7]
Posted by: Soren Wheeler
March 24, 2008 - 11:49AM

Blake,

Unfortunately, there's a little time lag between the show going on the radio and being available on the website or through podcast. But it will be up in the next couple weeks and we'll post a blog when it's ready.

Sorry for the wait.

[8]
Posted by: pffft
April 10, 2008 - 01:31PM
Seattle

Another great Radio Lab episode. Keep up the good work. Radio Lab is up there with This American Life as one of my top shows.

The Karen Keegan segment was especially good and quite moving.

[9]
Posted by: Snacky0
April 11, 2008 - 07:22PM

Great Show! I always look forward to the new episodes. I am a little confused about the link to the jewelry website.... Is that a mistake? Just curious - I wanted to see who was selling Pegasus wings.....

Thanks!

Snacky O

Leave a Comment

Please stay on topic, be civil, and be brief.
Email addresses are never displayed, but they are required to confirm your comments. All comments on WNYC are moderated. WNYC reserves the right to edit any comments posted on this site. Please read the WNYC.org Comment Guidelines before posting.

Your comment


* required
The information entered into this form will not be used to send unsolicited email and will not be sold to a third party.
 
Back to Episode

Web tools supported by
Print friendly format
supported by
Listen Live
FM 93.9 Windows 20k
MP3 32k
On Air: Jonathan Schwartz - The Sunday Show

Due to contractual obligations, Jonathan Schwartz - The Sunday Show is not available on our audio stream.

AM 820 Windows 20k
MP3 32k
On Air: A Prairie Home Companion
Shopping Online?
Start your Amazon shopping on WNYC.org and a portion of your total purchase goes to WNYC.


Audio Search

Search current and archival WNYC broadcasts. More

In The Spotlight
Radio Lab Blog
Radio Lab’s got a blog! Check out our rants and ramblings, hear bonus audio, and get all kinds of other goodies like ringtones and videos.
More
Radio Lab Email
Sign up for Radio Lab email updates

Tell Radio Lab What You Think
Have questions about the show? Ideas for topics for Radio Lab to investigate? Heard things you like? Don’t like? Let us know. We’d love to hear from you.

Email us at [email protected]

Most Emailed